产品货号：
Z16890
中文名称：
GBP1抗体
英文名称：
Anti-GBP1 antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GBP1 antibody |
| 指标别名 | GBP 1;GBP1;GTP binding protein 1;HuGBP 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF,IP,ELISA |
| 基因名称 | GBP1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human GBP1 recombinant protein (Position:R240-S592). |
| 实际分子量 | 68KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Interferons induce a large number of genes in their target cells,including those coding for guanylate-binding proteins(GBPs).GBPs,such as GBP1,are characterized by their ability to specifically bind guanine nucleotides(GMP,GDP,and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3.The 593-amino acid GBP1 protein shares 77% and 88% identity with GBP2 and GBP3,respectively.All GBPs,including GBP1,have a conserved N-terminal globular GTP-binding domain containing 2 consensus sequences and a third T(L/V)RD sequence not found in other GTPases.The GBP1 gene to the GBP gene cluster on chromosome 1p22.2.It is located telomeric to GBP2 and centromeric to GBP3.High expression of GBP1,GBP2,and GBP3 are in endothelial cells after stimulation with IFNG,TNF,or IL1B. |
| Uniprot ID | P32455 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | guanylate binding protein 1,interferon-inducible |
| 蛋白名全称 | Guanylate-binding protein 1 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 ImmunoPrecipitation (IP) 1:50 Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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